Search results for "Function analysis"
showing 10 items of 28 documents
Relationship between eating styles and temperament in an Anorexia Nervosa, Healtlhy Control, and Morbid Obesity female sample.
2014
Contains fulltext : 127209.pdf (Publisher’s version ) (Closed access) Objectives: Eating styles have been studied in both Obesity (OB) and Eating Disorders (ED), but they have not been examined in these two weight conditions together. The present study explores differences in eating styles in an Anorexia Nervosa (AN) and OB sample, compared to Healthy Controls (HC), and it analyses their relationship with Body Mass Index (BMI) and personality traits. Method: The total sample consisted of 291 female participants (66 AN, 79 OB and 146 HC). Evaluation: Assessment measures included the Dutch Eating Behaviour Questionnaire-DEBQ- and the Temperament and Character Inventory-Revised-TCI-R-. Results…
Maturational effects on newborn ERPs measured in the mismatch negativity paradigm.
2003
Abstract The mismatch negativity (MMN) component of event-related potentials (ERPs), a measure of passive change detection, is suggested to develop early in comparison to other ERP components, and an MMN-like response has been measured even from preterm infants. The MMN response in adults is negative in polarity at about 150–200 ms. However, the response measured in a typical MMN paradigm can also be markedly different in newborns, even opposite in polarity. This has been suggested to be related to maturational factors. To verify that suggestion, we measured ERPs of 21 newborns during quiet sleep to rarely occurring deviant tones of 1100 Hz (probability 12%) embedded among repeated standard…
The membrane distal half of gp130 is responsible for the formation of a ternary complex with IL-6 and the IL-6 receptor
1995
AbstractGp130 is the signal transducing subunit of the interleukin-6 receptor. Signaling is initiated by the complex formation of gp130 with IL-6 bound to the IL-6 receptor (IL-6R). We have subdivided the extracellular domain of gp130 in two parts and expressed the mutant proteins as soluble IgG fusion proteins in COS-7 cells. By studying the formation of the ternary complex we show that the membrane distal half of gp130 which contains a cytokine receptor domain is responsible for the interaction with the IL-6/IL-6R complex. Interestingly this is the same region which is believed to be involved in specific recognition of the related cytokines LIF, OM, and probably also of CNTF and IL-11.
Sex determination by discriminant analysis: an evaluation of the reliability of patella measurements
2004
Recently, a method which estimates the sex of unknown skeletal remains by discriminant function analysis of the patella has received much recognition. With seven simple measurements and a sexing accuracy of almost 84% this morphometric approach would be very suitable both in the forensic and anthropological context. In order to put this method to the test, 52 unfractured and non-pathological left and right patellae (26 males, 26 females) from a prehistoric skeletal sample were analyzed. In addition, 30 patellae were randomly selected which were not part of the original reference series. The first 15 (4 males, 11 females) had the same sample origin as the 30 target specimen but were of medio…
Contribution to the taxonomy of the family Campulidae Odhner, 1926 (Digenea) by means of a morphometric multivariate analysis
1996
Digeneans of the family Campulidae occur exclusively in marine mammals, particularly in cetaceans. Their taxonomy is confused, being based on adult morphology only. We used a multivariate discriminant analysis of morphometric data to provide new evidence on the taxonomy of the Campulidae. Measurements of 217 specimens from 21 species of all seven genera of the family were taken. The percentage of specimens correctly assigned into their own species was 96.3%. The first three discriminant functions accounted for most of the variation between the species, which were grouped together in suprageneric groups along the first and the second function. The ordination pattern observed conforms partly …
Artificial Neural Networks and Linear Discriminant Analysis: A Valuable Combination in the Selection of New Antibacterial Compounds
2004
A set of topological descriptors has been used to discriminate between antibacterial and nonantibacterial drugs. Topological descriptors are simple integers calculated from the molecular structure represented in SMILES format. The methods used for antibacterial activity discrimination were linear discriminant analysis (LDA) and artificial neural networks of a multilayer perceptron (MLP) type. The following plot frequency distribution diagrams were used: a function of the number of drugs within a value interval of the discriminant function and the output value of the neural network versus these values. Pharmacological distribution diagrams (PDD) were used as a visualizing technique for the i…
Application of multivariate statistics to the problems of upper palaeolithic and mesolithic samples
1987
Multivariate statistics (discriminant function analysis and principal component analysis) have been applied to a broad sample of Upper Paleolithic and mesolithic skulls. In addition to some methodological problems concerning the evaluation of missing data by principal component analysis, we discussed the possibility of misclassifications (14%).
CORPORATE BANKRUPTCY AND INSOLVENCY PREDICTION MODEL
2021
In any competitive economy, the risk of bankruptcy is pervasive. The research aims to contribute in improving the predictive power of bankruptcy and insolvency risk among companies by introducing new methods of processing and validation. This paper investigates the extensive application of the Z score model for predicting the economic-financial stability of Romanian companies in the manufacturing and extractive industries. A list of 37 financial indicators determined on the basis of the balance sheet data of 80 companies for the period 2015–2018 was used. Stepwise Least Squares Estimation through the Forward method allowed the identification of the most relevant ones. Canonical discriminant…
Parental and Infant Gender Factors in Parent-Infant Interaction: State-Space Dynamic Analysis.
2017
This study aimed to investigate the influence of parental gender on their interaction with their infants, considering, as well, the role of the infant’s gender. The State Space Grid (SSG) method, a graphical tool based on the non-linear dynamic system (NDS) approach was used to analyze the interaction, in Free-Play setting, of 52 infants, aged 6 to 10 months, divided into two groups: half of the infants interacted with their fathers and half with their mothers. There were 50% boys in each group. MANOVA results showed no differential parenting of boys and girls. Additionally, mothers and fathers showed no differences in the Diversity of behavioral dyadic states nor in Predictability. However…
Identification of residues in the putative 5th helical region of human interleukin-6, important for activation of the IL-6 signal transducer, gp130
1996
AbstractWe have previously shown that L58 in the putative 5th helical region of human interleukin-6 (IL-6) is important for activation of the IL-6 signal transducer gp130 [de Hon et al. (1995) FEBS Lett. 369, 187–191]. To further explore the importance of individual residues in this region for gp130 activation we have now combined Ala substitutions of residues E52, S53, S54, K55, E56, L58 and E60 with other substitutions in IL-6, known to affect gp130 activation (Q160E and T163P). The combination mutant protein with L58A completely lost the capacity to induce the proliferation of XG-1 myeloma cells, and could effectively antagonize wild type IL-6 activity on these cells. Moreover, the data …